Interferometric Reflection Imaging Sensor from Multiplexed Molecular Affinity Measurements to Counting Single Analytes

Ústav fotoniky a elektroniky AV ČR Chaberská 1014/57, Praha 8, Praha

Interferometric reflectance imaging sensor (iRiS) technology is based on interference of light from an optically transparent thin film —the same phenomenon that gives rainbow colors to a soap film when illuminated by white light. IRIS has two modalities : (i) low-magnification (ensemble biomolecular mass measurements) allowing for multiplexed affinity measurements and (ii) high-magnification (digital detection...